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PCOS
PCOS and insulin resistance: what the research actually says
The link between PCOS and weight isn't just about eating less. Insulin resistance changes how your body responds to food — and to GLP-1 medication.
6 min · January 2026Read
Honest, evidence-based writing on GLP-1 treatment, weight management, and hormonal health.
Most weight loss advice ignores the hormonal context that drives appetite, fat storage, and metabolism — especially in women. Here's what a consultant gynaecologist actually looks at when building your treatment plan, and why the standard calorie-deficit approach so often fails.
The link between PCOS and weight isn't just about eating less. Insulin resistance changes how your body responds to food — and to GLP-1 medication.
The hormonal shift of perimenopause changes where fat is stored, how hunger signals work, and how well you respond to conventional dieting. Here's the physiology.
Weight loss before IVF can meaningfully improve outcomes — but the timing and clinical approach matter. Here's what to consider before you start.
Moving to a new provider mid-treatment isn't as straightforward as it sounds. Here's what to bring, what to expect, and how to avoid restarting unnecessarily.
Reduced appetite sounds like an obvious advantage — but eating too little, and the wrong things, can undermine your results and leave you exhausted. A practical guide.
Tirzepatide's dual GLP-1 and GIP mechanism may offer particular advantages for women with PCOS and insulin resistance. Here's what the early evidence shows.
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